Journal Feed Weekly Wrap-Up

We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter.
Originally published at JournalFeed, a site that provides daily or weekly literature updates.
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#1: SCOUT RCT | 5 or 10-day Treatment for Pediatric UTI?

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This multi-center, double-blinded, non-inferiority trial found that short-course antimicrobial therapy had relatively low treatment failure rates compared to standard-course in children diagnosed with UTI who showed clinical improvement after 5 days of antibiotics.

Source
Short-Course Therapy for Urinary Tract Infections in Children: The SCOUT Randomized Clinical Trial. JAMA Pediatr. 2023 Jun 26:e231979. doi: 10.1001/jamapediatrics.2023.1979. Epub ahead of print.

#2: OPAL RCT – No More Opioids for Back Pain

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Opioid pain medications offer no benefit compared to placebo for patients with acute back or neck pain.

Source
Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial. Lancet. 2023 Jun 27:S0140-6736(23)00404-X. doi: 10.1016/S0140-6736(23)00404-X. Epub ahead of print.

Spoon Feed
There is practice variation in the treatment of patients with intermediate-risk pulmonary embolism (PE). The treatment threshold for which fibrinolytics should be added to standard anticoagulation in hemodynamically stable patients at risk for decompensation has been a focus of PE research for the last decade.

Source
Treatment of Intermediate-Risk Pulmonary Embolism. N Engl J Med. 2023 Jul 13;389(2):184-187. doi: 10.1056/NEJMclde2301330.

 

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