Journal Feed Weekly Wrap-Up

We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter.
Originally published at JournalFeed, a site that provides daily or weekly literature updates.
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#1: Does Stress Ulcer Prophylaxis with a PPI Work?

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An international, multi-center RCT found that administering pantoprazole to intubated ICU patients lowered the rate of upper GI bleeding compared to placebo.

Source
Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation. N Engl J Med. Published online June 14, 2024. doi:10.1056/NEJMoa2404245


#2: GRACE-4 – New Guidelines for Alcohol Withdrawal, Alcohol Use Disorder, and Cannabis Hyperemesis

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GRACE-4 is packed with practice-changing recommendations for patients with alcohol withdrawal syndrome (AWS), alcohol use disorder (AUD), and cannabinoid hyperemesis syndrome (CHS).

Source
Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department. Acad Emerg Med. 2024 May;31(5):425-455. doi: 10.1111/acem.14911. PMID: 38747203.


#3: Does Topical Diclofenac Work for Acute Low Back Pain?

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Unfortunately, topical diclofenac did not demonstrate substantial pain control and provided no added benefit, even when co-administered with oral ibuprofen for specific patients with acute low back pain.

Source
Topical Diclofenac Versus Oral Ibuprofen Versus Diclofenac + Ibuprofen for Emergency Department Patients With Acute Low Back Pain: A Randomized Study.Ann Emerg Med. 2024 Jun;83(6):542-551. doi: 10.1016/j.annemergmed.2024.01.037. Epub 2024 Mar 2. PMID: 38441515

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