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Journal Feed Weekly Wrap-Up

We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter.
Originally published at JournalFeed, a site that provides daily or weekly literature updates.
Follow Dr. Clay Smith at @spoonfedEM, and sign up for email updates here.

#1: Could Paralyzing Before Sedatives Increase First Pass Success? 

Spoon Feed
This study utilized Bayesian analysis and found that when paralytic medications were administered before sedatives during ED intubation, there was an association with decreased first attempt failure rate.

Source
Effect of administration sequence of induction agents on first-attempt failure during emergency intubation: A Bayesian analysis of a prospective cohort.Acad Emerg Med. 2024 Oct 18. doi: 10.1111/acem.15031. Epub ahead of print. PMID: 39425254

#2: What Migraine Drugs Are Most Effective?

Spoon Feed
Triptans (eletriptan, rizatriptan, sumatriptan, and zolmitriptan) were found to be most effective in a systemic review and meta-analysis comparing the efficacy and tolerability of 17 oral medications for acute migraine management.

Source
Comparative effects of drug interventions for the acute management of migraine episodes in adults: systematic review and network meta-analysis. BMJ. 2024 Sep 18;386:e080107. doi: 10.1136/bmj-2024-080107. PMID: 39293828

#3: What’s the Real Half-Life of Troponin Elimination?

Spoon Feed
Authors used a novel method to determine cardiac troponin (cTn) elimination and found the half-life median range was 134 to 239 minutes, which is 5-16 hours shorter than results previously reported.

Source
Half-Life and Clearance of Cardiac Troponin I and Troponin T in Humans. Circulation. 2024 Oct 8;150(15):1187-1198. doi: 10.1161/CIRCULATIONAHA.123.066565. Epub 2024 Sep 10. PMID: 39253802

 

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