#1: What Happened to Plain Albuterol? Meet the New Combo Inhalers
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According to a large number of RCTs, both pediatric and adult patients seem to have better asthma control with combined asthma therapy: inhaled corticosteroid (ICS) and short-acting β-agonists (SABA) or long-acting β-agonists (LABA) as opposed to a SABA alone.
Source
Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis. JAMA. 2024 Oct 28:e2422700. doi: 10.1001/jama.2024.22700. Epub ahead of print. PMID: 39465893
#2: Sinusitis Guidelines Are Outdated, What’s Changed?
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While updates to national guidelines have not been made in the past 10 years, recent data suggest that children with mild acute bacterial rhinosinusitis (ABRS) may not need antibiotics, and that when indicated, amoxicillin has similar efficacy to amoxicillin-clavulanate.
Source
Antibiotics for Pediatric Acute Bacterial Sinusitis. JAMA. 2024 Oct 16. doi: 10.1001/jama.2024.2018. Epub ahead of print. PMID: 39412765
