#1: Early Shock – Better VF Outcomes in OHCA
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For every minute of delay to shock in ventricular fibrillation (VF) arrest, the proportion of successful first shocks decreases by 6%. When the first shock is delivered within 2 minutes, success is 95% but drops to 75% when the delay exceeds 6 minutes.
Source
Association Between Delay to First Shock and Successful First-Shock Ventricular Fibrillation Termination in Patients With Witnessed Out-of-Hospital Cardiac Arrest. Circulation. 2024 Oct 27. doi:
#2: Should You Check Troponin in SVT?
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This meta-analysis of 500 patients with SVT found that while 46% had elevated troponin levels, only a small proportion experienced major adverse cardiac events (MACE) or required significant additional cardiac testing, highlighting the importance of clinical judgment, as troponin elevation does not always predict worse outcomes.
Source
The Role of Troponin Testing in Patients with Supraventricular Tachycardia, Systematic Review and Meta-Analysis. J Emerg Med. 2024 Nov;67(5):e402-e413. doi: 10.1016/j.jemermed.2024.05.010. Epub 2024 May 19. PMID: 39242347
#3: Hyponatremia – Are We Correcting Too Slowly?
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Slow correction of hyponatremia was associated with increased in-hospital mortality and length of stay in this meta-analysis of observational studies.
Source
Correction Rates and Clinical Outcomes in Hospitalized Adults With Severe Hyponatremia: A Systematic Review and Meta-Analysis. JAMA Intern Med. 2024 Nov 18:e245981. doi: 10.1001/jamainternmed.2024.5981. Epub ahead of print. PMID: 39556338